AMD Athlon processors work best with AMD motherboards. If you are worried about the efficiency of your processor, it is best advised to use Dual AMD motherboard with your AMD Athlon processors. As the dual AMD motherboards work best with all the AMD processors and are the most appropriate choice as far as motherboards are concerned which works well with the multiprocessor motherboard. AMD processor do not perform well with multiprocessor motherboard, only AMD Athlon processor is the recommended choice by the technical staff to give you maximum performance by your motherboard and processor.